Serum sickness

What does the combination of erythema multiforme, fever and swollen joints equal? If you answered a visit to the Emergency Department you’re only partially correct. Serum sickness like reaction is a delayed type hypersensitivity reaction that often occurs 7-10 days after starting a course of antibiotics. Learn how you can recognize it and differentiate it form more serious illness like Stevens Johnson Syndrome in this episode of PEM Currents, the Pediatric Emergency Medicine Podcast.